Running the game executable with -nomoviestartup (step 6 in bartch's answer) solved the problem for me.
My problem was a consistent crash when exiting the mission summary screen at the end of Kasumi's mission. Game installed through steam, DLCs from Bioware's site.
I'm using Steam. I've found the .exe but when I go to properties I don't see where I can edit the Target as usual. I'm running as admin.
A reply to an old post for Steam users, but I had the same issue when I reinstalled ME 2 and all the DLC with steam. And what worked for me was to view the library< right click on the game < select properties < then click on Set Launch Properties< then type -nomoviestartup in the blank field < Click OK and launch the game.
THANK YOU THANK YOU THANK YOU!
This saved me when I was stuck in Lair of the Shadow Broker. Didn't get to see Liara come to the ship but none of the other options work.
For SEO optimization: Mass Effect 2 Lair of The Shadow Broken Crash When Leaving Ship Steam see the above solution provided by bakgrind. Also, this is properties in Steam, not in the application itself.
