I can't say anything about ABS, I always turn off steering/braking assistance.
And because I got my driving licence when ABS was not widely available in cars, I learned how not to rely on such features 😉
I wouldn't recommend to set BB to 50, sometimes you really need front-end to help you stop the car for better rotation into a corner. On the other end, default setups have very high BB, around 60, which doesn't fit my driving style.
So I guess it's like @mariohomoh said, it's up to you how you want to enjoy the game 😉
Just FYI, I usually go for setups between 56-52 because I gradually break into corners and I often get on throttle before apex 😉