Game fails to load, "Failed to initialize the physics system."

Thank you! repairing Physx worked

Wish I found this post 3 and a half hours ago. Youre a life saver man

hey did you ever figure this problem out just bought the game but cant get it to load cause of this error

When i went to repair Nividia - Phys X it came up with an old file path of steam... so i uninstalled it - then right clicked on Mass Effect 3 in Origin file and clicked repair - i was then able to load in

Trying repair both game and PhysX. Still doesn't working. Have someone any ideas yet?

EDIT: Finally working.

Mine still shows the same error.

Edit: Same with the dude above.

I have this problem, repairing the PhysX program did nothing. I have a 960 and the latest drivers

Just repairing Physx didn't work for me, had to repair ME3 install from Origin library too. That did the trick!

I don't seem to have a repair option. When right clicking, I only have the option "Uninstall/change" which when clicked will bring up the uninstall window. What do I do?

does not work there is no physx thingy.