Solved

Wow, that sounds incredibly frustrating! It’s really disappointing when an update causes so many issues, especially when it affects core parts of the game like saving and using the Simology panel. Since you've already tried removing CC and mods with no success, here are a few more steps that might help:

1. Clear Cache: Clearing the EA app’s cache can sometimes resolve strange issues. Go to the app's settings and look for an option to clear the cache.
2. Backup and Reset: You could try backing up your saves and resetting the game’s user files. This can be done by moving your 'Sims 4' folder from Documents > Electronic Arts to your desktop and then starting the game fresh.
3. Check for Updates: Keep an eye out for any hotfixes or patches from EA. Sometimes, issues like these are widespread, and the devs are already working on a solution.
4. Reinstall the Game: If all else fails, a full reinstall might be necessary, though I know that’s a hassle.

I really hope EA releases a fix soon, especially since the game didn’t work even after removing mods.