Game Crash after Patch 2.0.1

Before current update no Crashes occured.
Now i have problems!!!
Why?

I edited the machine GUID registry key, reinstalled game, repaired game, activated DirectX 12, and I have the latest Treiber

Processor: Intel(R) Core(TM) i9-10900KF CPU @ 3.70GHz (20 CPUs), ~3.7GHz
Memory: 65536MB RAM
Available OS Memory: 65400MB RAM
Page File: 11067MB used, 64061MB available
DirectX Version: DirectX 12

DWM DPI Scaling: Disabled
Miracast: Available, no HDCP
Microsoft Graphics Hybrid: Not Supported
DirectX Database Version: 1.4.1
DxDiag Version: 10.00.25197.1000 64bit Unicode

Card name: NVIDIA GeForce RTX 3090
Manufacturer: NVIDIA
Chip type: NVIDIA GeForce RTX 3090
DAC type: Integrated RAMDAC
Device Type: Full Device (POST)
Device Key: Enum\PCI\VEN_10DE&DEV_2204&SUBSYS_38841462&REV_A1
Device Status: 0180200A [DN_DRIVER_LOADED|DN_STARTED|DN_DISABLEABLE|DN_NT_ENUMERATOR|DN_NT_DRIVER]
Device Problem Code: No Problem
Driver Problem Code: Unknown
Display Memory: 57048 MB
Dedicated Memory: 24348 MB
Shared Memory: 32700 MB
Current Mode: 2560 x 1440 (32 bit) (144Hz)

Card name: NVIDIA GeForce RTX 3090
Manufacturer: NVIDIA
Chip type: NVIDIA GeForce RTX 3090
DAC type: Integrated RAMDAC
Device Type: Full Device (POST)

Driver File Version: 31.00.0015.1694 (English)
Driver Version: 31.0.15.1694

Edit:

@EA_Atic told us to follw these steps: https://www.easy.ac/en-us/support/game/issues/guide/
But i already have the newest Win Version and the newest Nvidia Driver