Lost settings

Title says it all.  Started the game, played for a while, closed the game.  Started the game from Origin again later, and it's acting like it's a first-time start.  Resolution is wrong, making me go through all the calibration and game demo again.    Restarted the game, killed Origin and restarted it, rebooted the PC, no luck.  What happened to all my settings?  How can I get them back?