Game Crash in Sanctuary Tower

I play ME3 on PC.

I have played through a number of times without issue, but recently I installed the Citadel DLC and was able to play through that fine. I went back and started a new game and everything has been going fine until I hit a certain point in the Sanctuary Tower. At this point I have received the last recorded message from Miranda, climbed up the ladder and cleared the corridor. This is just before getting on the short tram ride. The game crashes every time I walk through the doorway. I've tried several different times making attempts walking, running, walking backwards and sideways and at an angle. I've tried reloading my quicksave just before going through the corridor and a slightly earlier autosave just after clearing the corridor. Crashes every time. I had an issue very early on in ME3 before any patches where it would sometimes crash at this point, but haven't had it with at least a half-dozen play thoughs since.

As an aside I have double checked that my graphics drivers are up to date.

App event log

Log Name:      Application
Source:        Application Error
Date:          3/7/2013 5:34:56 PM
Event ID:      1000
Task Category: (100)
Level:         Error
Keywords:      Classic
User:          N/A
Computer:      ***
Description:
Faulting application name: MassEffect3.exe, version: 1.5.5427.124, time stamp: 0x50d4cab0
Faulting module name: MassEffect3.exe, version: 1.5.5427.124, time stamp: 0x50d4cab0
Exception code: 0xc0000005
Fault offset: 0x00243841
Faulting process id: 0x6b8
Faulting application start time: 0x01ce1b83e13652f2
Faulting application path: ...\Mass Effect 3\binaries\Win32\MassEffect3.exe
Faulting module path: ...\Mass Effect 3\binaries\Win32\MassEffect3.exe

Also as a note I did try restarting the Sanctuary mission from the beginning and got the same thing.