Mass effect 2 suddenly won't launch

Okay, I did the following:

Reinstalled EA app. (Origin won't even <install> now, so HAVE to use EA App.)

Reinstalled Mass Effect 2

Installed Visual C 2005. Tellingly, it never asked to repair, which indicates it was never installed in the first place.

Renamed the executables.

And after all that, ME2 FINALLY worked. However, I have a secondary problem. I had a stroke some years ago, and now need to use WeMod just to play the game at all. With the renamed executables WeMod won't run, so I have to use an unmodded ME2. Is there a way to get ME2 working without renaming files?

Or will I have to buy the Legendary edition? Hope not, Paying for the game twice blows.

There should be an option in WeMod to change the file path for ME2.  

1. Click the down arrow next to the blue "play" button in wemod.
2. It should say "select game source" look at the bottom of the list.  There should be a box to drop a file for manual assignment of the .exe to run the game.
3. drag and drop the .exe file from your steam or origin file path into the box.
4. Run the game.
5. Click play as usual.

There should be an option in WeMod to change the file path for ME2.  

1. Click the down arrow next to the blue "play" button in wemod.
2. It should say "select game source" look at the bottom of the list.  There should be a box to drop a file for manual assignment of the .exe to run the game.
3. drag and drop the .exe file from your steam or origin file path into the box.
4. Run the game.
5. Click play as usual.