Solved
[PC] Mass Effect 3 freezes after resume
After I finished the game I decided to play the DLCs, so I downloaded them. In the main menu when I click on resume, the game freezes, and nothing can be done, unless I ended the game in the task man...
First, open your Task manager > click on "Options" > enable "Always on top".
Now you should be able to see the task manager even if ME3 is in full screen mode.
Did you tried to repair the game? (in Origin > Game Library > right click ME3 > Repair)
If that don't helps, go to your "Documents\BioWare\Mass Effect 3" folder and move the "Save" and the "BIOGame" folder to your desktop. > Test.
