@deaashkea If Origin doesn't open at all, click on the Apple icon in the upper left corner of your screen and select System Preferences. Under Security & Privacy, you should see a notice about Origin being blocked. (If it's not there, quit System Preferences, try to open Origin again, and then go back and look.) Click the lock icon in the lower left corner of the window, enter your password to make changes, then click the option to allow Origin to open anyway.
If Origin does open but doesn't work normally, there are a few other steps you can try, even after the reset and disabling proxies didn't work. Sign into Origin using your full email address or just your username, whichever you haven't been doing.
Please also temporarily disconnect any USB devices, just to see whether it helps.
If these steps don't work, you can try the others in this Origin troubleshooting thread:
https://answers.ea.com/t5/Technical-Issues-Mac/READ-FIRST-Origin-Troubleshooting-and-Information/m-p/5371661#M3387
If nothing else makes a difference, create a new admin user account on your Mac (make sure the name uses only letters and numbers, no special characters), and try to login using that account.