I'm assuming it's a Celeron E3400? Doesn't matter.
A 3450 is a tad slower than an HD3000. Ouch ;(
http://www.tomshardware.com/reviews/gaming-graphics-card-review,3107-7.html
That shows the 3450 is 10 (!!!) tiers below the the lowest 8800GT.
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I'd try updating your drivers maybe?
http://support.amd.com/en-us/download
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Try Windowed or Borderless Modes.
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I'm thinking the frame rate is sooo low it just isn't accepting your clicks until well after the fact maybe?
Turn everything to lowest possible. Put your resolution to like 1024x768.
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Left Ctl + R shows your FPS on screen.
They never made a 2GB 3450... they made 256MB versions and 512MB I think... that's some weird system specs all around holy cow.
