I encountered the same problem. I'm on latest Windows 7. The above solution to make the executables run as administrator didn't help me. However, I was able to fix the problem by closing all the other open programs (Including Chrome), as well as close as many of the hidden taskbar tray programs as I could. It seems that SimCity isn't good at maintainig its window focus and other processes can easily **bleep** it away.
I just started having this problem on my brand new surface tablet, after successfully running the game a couple times. I ran through this thread and tried a couple of suggestions, and found that what was causing the problem was the onedrive automatic synching process, which was in the hidden icons tray. I paused the file synching and now it works just fine.
Still having issue, any EA fix?
