Do you take them? I used to but not so much anymore I find them a little too cheaty now and they make the game too easy and boring for me. Especially the ridiculous ones like 'steel bladder'
There are a few that I try to get right away. In my current save, I have to get them all eventually as it is a challenge where you max all skills and skill challenges, careers, and some other things. In a normal save, Steel Bladder is always my first one. Other than that, it is up to what ones I think the Sim needs.