I hear it increases loading time, so I disable it. I'm in the habit of loading a save and walking away from my computer long enough so that the game is loaded by the time I return. The interactive screen wouldn't benefit me anyways. I save with the game paused, and I think my NRaas mods load the game in pause mode regardless so I don't worry about my simn on free will unattended. :p I also play in a window so if I'm actually at my computer while the game loads my attention is on various websites (like this one) instead of the loading screen.