I got this error code mid-gameplay. I'd moved my family out of Britechester when it got bugged out in the June 3/4 updates, and avoiding it fixed my issues. Since the June 10 update was supposed to fix it, after I downloaded the update I sent the young adult in that family to college. I've made it most of the way through a semester of classes (did all the finals stuff, but didn't get grades), and when I sent him back to University Housing from Larry's Lagoon all of a sudden it kicked me back to the world select screen with this error code. When I relaunched the game and clicked on my guy at the University Housing, the logo was a green danger icon (triangle with an exclamation mark inside it) and it said the lot was "incomplete."
I've tried loading it after I removed CC/Mods (all downloaded pre-June 10 update, and I played for several hours on the 10th and today without issue with them), still won't load correctly, not that anything I had was applicable to a Sim in college.
EDIT: Playing around with it more, I can't load ANY of my households (the Britechester guy and the person he left at home in Windenburg). I also tried making a new household in Strangerville, and it let me create a sim and pick a lot for him but clicking the lot and then clicking play produces the same error.
Random info you might need to know for fixing: I currently own Discover University, Seasons, City Living, Get Together, Get to Work, StrangerVille, Laundry Day, and the free Holiday Celebration pack. I am on a MacBook Pro running MacOS Catalina 10.15.5. I am running the most recent version of Sims 4 and tried running the game with CC removed. I tried the repair button in Origin but it was useless, as it usually is for most things. I am not sure what to try next.