Broken Game after 8/2 patch

Since the 8/2 patch my game is broken. What happens is that the game loads ok, and i can load a save ok, but once I am in live mode, after a very few interactions (clicking on an object, sim, location, or icon), the game becomes unresponsive, I get the spinning wheel and have to force quit the game. After the first patch, I carefully updated all my mods and tested the game. I had some issues with known bugs but the game played ok. Then after the second patch this problem appeared. I have removed all mods, repaired the game twice and tried a folder refresh- none of these attempts have helped. I don't know what to do next.