I did a full refresh, and it seems to have worked for the most part. I am now saving *SEVEN* times each time I save (Save as ..., Save x5, Save as ...) but I have *finally* made it past a week, even when testing fate and doing a few loading screen triggers like manage world, exiting game and reentering the game, only thing I haven't tried yet is CAS because I simply forgot before turning things off for the night. I had a hiccup, with time reverting to another day, ONCE after but I chalked it up to me fumbling a step on the saving process (thus why I now save seven times each time, hoping that will keep it in check. I do not for the life of me trust the simple single save at this point in time, even with apparent improvements.) I honestly don't know if it is fixed or not still but right now it seems to be smoother sailing, at least.
My original file is beyond saving. I am pretty sure I accidentally killed it somehow during the first attempt at cleaning out the mods and testing with it, because it simply won't load anymore, or if it does it is so astronomically slower than anything else on a fairly competent gaming PC, I consider it as infinite loading. With or without mods, I tested a few times back and forth before abandoning it entirely.
What I am talking about appearing to be functional now is the fresh save file I made after the file refresh, with the same characters technically speaking but taken from the very first gallery save I had of them, dating back before I had any issues (and I suppose before anything other than CC eye colors had affected them).
There's so many variables presenting themselves I don't know whether to cry or laugh. There were no babies in the picture for me so I can't comment on that, but reward points, skill progress and work progress were casualties in the worst scenarios for me. I did not notice anything relationship wise but my active household was basically all best friends for quite some time prior, so it's hard to tell, I am awful at paying attention to relationships with NPC's as I usually don't care much for them.