Hi @eemiliak ! The OP mentioned that the issue was with the Slice of Life mod. Do you have that in your game? If so, try removing that first. Otherwise, there is really no way to know which mod is causing this problem without testing them all and also deleting the localthumbcache.package file located in the Documents / Electronic Arts / The Sims 4 folder before opening the game for testing. Since you have a lot of mods/CC, the 50/50 method works best.
1. Divide your mods/CC in half (maybe make a folder on your desktop to hold the half you're taking out).
2. Delete the localthumbcache.package file again, before opening the game with the half you're testing,
3. If the game works with that half, test with the other half. (Again, delete that cache file before opening)
4. Once you know which half is causing the issue, divide those in half and test again (delete the cache file again).
5. Repeat the process until you find the culprit.
Since you mentioned having MCCC, you might also try using that to compensate for relationship issues. Try clicking on a computer then MC Command Center>MCCC Settings>Relationship Settings>Friendship Difficulty Adjustment OR Romance Difficulty Adjustment then choosing an option to enhance the speed at which your sims gain relationship points.
Realistically, you may want to do a bit of "spring cleaning" and reduce the amount of CC / mods you've installed. With such a large sized mods folder, chances are there are a lot of things that are broken and/or haven't been updated. Perhaps you could spend some time removing things you're not actually using, then test the things you want to keep. This may take some time, but it will be worth it to make sure your game runs more smoothly.
