I've been playing around with settings and I'm not sure how many people this will work for (the solutions to this problem seem to differ from person to person), but I'll put it out there anyway.
I set all my settings back to how they originally came (there's a button for that called 'revert to original settings' I think), turned laptop mode off, turned edge smoothing to low, turned vertical sync on, set objects and sims to high/very high in graphics, and didn't change anything else. For those who use CC, enable script mods again, too. The game still looks relatively good for me with all these settings.
Have played about 5 hours of gameplay since doing this, and only now the flickering is starting to come back, although it's mild and tolerable. If it starts to get bad again, I might try it all again and see if it temporarily fixes it again.
If these specific settings don't work, I think you might have to play around with your settings a bit. So, take note of what your settings are set to (in case you want to change them back), revert back to the original settings that came with the game, and start turning things off/on in order of priority. E.g, if the game looks terrible without edge smoothing, enable that first and then start playing around to make that work.
Hope this is helpful to someone!
