Cant click on certain things

@Anidup

OK if changing resolution doesn't help - it looks like mods/CC related problem or some configurations files in your game folder could be damaged after an update.
Go to Documents/ElectronicArts - inside will be The Sims4 folder
Step 1. Rename The Sims4 folder to "The Sims4 old"
Step 2. Fix the game in Origin
Origin/Library - right-click on TS4 - option "Repair game"
You have to wait until Origin will fix all packs, not only the base game.
Step 3. Turn on the game - a new game folder will be created and you will have two - one old, one new
Step 4. Check if you still have this problem in the newly created game folder.
If the problem disappeared
Step 5. Delete in the new game folder following folders:
"saves" and Tray.
Step 6. Go to "The Sims 4 old" folder and copy - your "saves " folder.
Step. 7, Paste this folder in a newly created game folder.
Step 8. Do the same with Tray folder and TrayDeleteItems file
Step 9. Check if there are newly updated version mods you are using.
Then copy and paste your mods and CC from old mods folder to the new one. First copy the scripts mods every time checking if the game is working properly. If you have a lot of CC try 50/50 method ( divide your CC into smaller batches for example 50 pieces in one subfolder and check these subfolders one by one)
Step. 10. If all is OK - delete The Sims4 old folder.

Your saves and library will stay as it was.