@thegrape2005
Is this just an issue with Sims 4? Meaning do you have problems with other games or programs?
If it's just Sims 4, try these tips:
1. Quit fully out of game, and restart the game. Or Quit out of game and restart the computer to refresh it. -- This helps with the Number Keypad Hotkey not working issue.
2. Deactivate Origin in Game -- Open Origin, Select Origin > Application Settings > Origin In Game tab and click the on/off switch to disable Origin In Game. - This deactivates Origin In-Game, as it has been known to cause problems with games.
3. Repair Game:
In Origin > Games Library, right-click on Sims 4 and select Repair. It does not make any changes to the saved game files. Meaning that your saved games are safe, they won't be deleted. If you'd like you can copy the Sims 4 folder to a USB key.
4. If you have mods or custom content installed, move the mods folder to the desktop. Delete the game cache and the localthumbcache.package from inside the Sims 4 folder and launching the game and play a new save to test.
-- Even if you don't play with mods or custom content installed, it's a good idea to delete th game cache and the localthumbcache.package from the Sims 4 folder to help with troubleshooting.
How to Delete Cache Files
https://sims4.crinrict.com/en/2014/09/delete-cache-files/