Re: The Sims 4 Won't Start in normal mode but can start in Safe mode

This means that some of the software on your PC is preventing the game from functioning properly.

Have you added the game and Origin to the whitelist of your firewall and antivirus?

Also, what if you disable Just-in-time? Follow these steps:

http://msdn.microsoft.com/en-us/library/5hs4b7a6.aspx