Press the ''shift'' key for 9 times consecutively. And you will solve the problem.
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Hitting alt-W twice helped me.
Ran into this problem on Windows 10 Pro.
Solution for me was to go into C:\Program Files (x86)\Origin Games\Mass Effect 3\Binaries\Win32 , right click on MassEffect3.exe, go to properties, and change compatibility mode to Windows 7, and check the box for "Run as Administrator".
