@IIIWhiteWolfIIIAre your elbows 90 degrees to the table while sitting? Make sure feet are flat on the ground, and the table is low enough to get that 90 degrees. I personally remove the plastic feet from the ikea legs to lower it half an inch or so for an example.
For the mouse, I find something with a hump too far forward, or dead center uncomfortable. It’ll pinch my palm slightly against the mousepad. Like it doesn’t hurt, but messes with my aim. If that applies to you at all, I’d recommend something like g pro Superlight, just anything with the hump further back. I also claw grip rather than palm. Maybe experiment with different grip styles to see if that helps.