Crosshair not aligned to center of screen

I recently turned my gaming monitor's crosshair overlay on that shows a reticle in the center of the screen. The in-game crosshair is always slightly to the right of it, which means the game's reticle is not centered, which affects my aim. My fullscreen resolution is correct, using crosshair projection OFF if that matters. I turned the crosshair opacity in game to 0 so that the reticle was invisible and relied only on my monitors crosshair overlay, my shot accuracy and gameplay immediately improved. Is there something I can do to make sure my in game crosshair is aligned to the true center of my monitor instead of being offset?