I'm having the same issue and its especially frustrating because I was able to play for 20 hours without problems.
Then a few days ago I started hard crashing, first in game then right upon startup before even compiling shaders. (The pre-rendered video wouldn't even load it would be all black on the loading screen).
I tried so many 'fixes', reinstalled game and drivers, system settings. What finally fixed it was uninstalling HD textures... but that lasted a day or two... I could play a few games fine... until the last patch which maybe broke it again?
It's ridiculous that this is literally unplayable.