Game wont launch since March 27 Update

Since the Patch 1.2.2.5 the game wont even launch, had an issue that was the same as when the beta was launched, then i updated bios and Windows, and still had the same issue(cant recall the long winded text, but was relating to amd drivers, i have Nvidia GPU) then reinstalled the game now this attached is all i see after reinstalling the game, no boosts of any nature on equipment XMP profile also not enabled, any ideas on how to get into the game again?