After trying to repair the game, update punk buster, delete the profile folder, try 32bit launcher vs 64bit, uninstall/reinstall AMD CCC/driver manually, (and every other combination and suggestion) the only thing that worked was the DDU (Display Driver Unistaller) DDU v15.5.1.0. Just Google it and download. You will need to launch it in SafeMode after you unzip and install. Its pretty much dumb proof, just follow the prompts and let it do its thing. I'm back to using Mantel, Ultra setting with crossfire, ZERO issues. BAM!
AMD A10-7850K
ASRock FM288X Extreme6+
32GB DDR3 2133
MSI R7 370 Gamming 4GB (x2 Crossfire)