Had the issue myself and after a few playthroughs I have tried the following:
Tried the suggested save+repair game in Origen - didn't work (only have keyboard/mouse so can't deselect controller)
Changed resolution and changed between fullscreen and windows mode - didn't work
The only thing I can get to repeatedly solve the problem is to go into "Graphics" and change the "Graphics quality". If I put it to automatic it consistently fails (automatic is high on my computer) - if I put it to low or medium it works fine.
Hope this helps someone.
Still not working for me! Please patch asap!
This is seriously one of the most absurd bugs. All sorts of strange weird tricks people are able to do to get it to work and some of us who no matter what it doesn't work. Crappy programming and even worse testing/quality control. I was singing high praises for this game before this and now I will be telling everyone to avoid it. What a let down.
