System Interrupts - freezing / stuttering

This is ridiculous, the game is virtually unplayable in this state

I tried a clean boot, switched from avast to AVG and nothing works.

Is your graphics setting Mantle or DirectX? Mantle did a heavy load on my PC when I tried it so I switched back to DirectX.

I'll be honest, I'm not even sure how to do that!  Sorry, I'm pretty useless, I hardly ever mess around with my settings except in game and could not see any options to choose such settings in game.

Main menu, Options, Display, Graphics Api. If you see there something else than Direct3D 11, change it, restart game.

Please post your dxdiag ( dxdiag instructions ). Thanks 🙂

Okay, please find a link below to my dxdiag.

http://hastebin.com/wogusugile.tex 

Are you using the Xbox controller to play the game? I've heard some people have had issues with controllers (not something I've really paid attention to, so don't remember what sort of issues), but maybe try removing the controller, see if that helps? (Quick and easy thing to test, anyway).
Your system meets the system requirements for the game, so it shouldn't be anything like that.
If you think the system interrupts thing is causing the issue, you might want to try Microsoft or Alienware (since according to your dxdiag that's who built your computer).
I've also noticed you've got a few errors down the bottom of your dxdiag, several to do with Windows Update. So perhaps Microsoft would be your best bet. Unless someone here has a solution. 🙂

I do use an Xbox controller so I will try that when I get a chance, thank you for your help and suggestions, I will see what I can do and hopefully get the game running properly!

Okay, I believe I have fixed the problem, at least so far, touch wood!  In case anyone else is having this problem maybe this will help.

I noticed the problem began occuring when playing other games and became more frequent, I put this down to the fact DAI forced me to upgrade my graphics driver and previously I had never updated it because, well, if it ain't broke don't fix it!  After spending a lot of time testing different drivers I finally found one that appears stable.  For me it was Nvidia 344.75.  I tried many later drivers than this and each time the problem kept occurring.  My graphics card is Nvidia GTX 660, I guess if people are having this problem and their system meets the minimum requirements to run the game then try using different drivers and hope you find one that works.

I assume most people will already know this and it is probably quite basic but maybe this will help someone.