Yeah i'm f.ex. too left-handed. My left hand is on the arrows keys (to move) and my right hand on the mouse (naga raza trinity mouse) where i bind normaly my spells (here in DAV 1-3 Main Spells, 4 the Ultimate, 5 Dodge and on 6 Block/ShieldBubble) and on the "RighShift" my sprint, that can click it with the ring finger :D
A mate of me is too left-handed but he does the opposite. Right hand on arrow keys to move and left hand on the mouse.
But for both of us it no fun to play without using the arrow keys to move.
And with third party software to rebind, you have a lot of problems when the program runs long or you push to often they keys then it starts to bug f.ex. "auto run" or "movement freezes" for few seonds etc. And if you edit the files directly, you get the whoobly camera problem, this is too fixable but indirectly.
So i HOPE to of a fast hotfixe!