Error Message "Failed to find default engine .ini file to retrieve My Documents"

@Puredpatata 

It seems the game can't access or create the Game folder under "Documents\Bioware\Mass Effect". 

That can be because of "Controlled folder access" of the Windows Defender, a third party virus scanner blocking the operation, or missing permissions.

• Run Origin and the game as administrator.
• If it don't works, look if "Controlled folder access" in the Windows Defender is active, and if so disable it or create a exception for ME1 and Origin.
  
  
• If it is not that, deactivate the virus scanner for testing purpose. If it works, create a exception for ME1 and Origin.