mass effect 2 does work on windows 10 , you have to goto the main game folder of mass effect 2 and for both mass effect2.exe 's right click and them and goto properties and click on compatability and select windows 8, and run as administrator , click ok on them both, and make a shortcut of the 2nd mass effect 2.exe down in the game folder on the desktop, and it will load everytime no issues, but from time to time it will crash once in a blue moon, but it works , i;ve just done the game, but mass effect 3 is not even loading at all, mass effect 1 i had to use a crack to get it to work on windows 7,8,10 and running it under windows 7 emulation with administrator on, might go back to windows 7 at this rate lol. hope this helps.
Have they any idea how pathetically dumb they appear to be. ME and ME 3 will work on windows 10, but apparently it's just too complicated for them to get ME 2 to work on win 10. They knew win 10 was going to replace all previous versions of windows and too prepare for it.
If you are using Origin, you can rename or move two files MassEffect2.exe and MassEffect2.par. Then let Origin repair files. This worked for me, and I am still running the latest Windows 10 betas.
I have a hard copy outside of origin. Game runs well on high settings, but alas, no saves. Tried all the compatibility modes and admin options and a reinstall. nowt.
Found a solution for my problem. Apparently Windows 10 set folders to read only. One has to manually disable this option in save file properties, and apply, also set sharing options to admin with control. Worked on my account fine. Glad to say, playing again, first time for a while. Awesome game. Windows 10 is good also.
I just encountered the issue... tried everything to get it working..
The only thing that works for me is to go into Mass Effect 2\Binaries and double click ME2Game.exe to launch the game.
Only drawback I found was that every time I start the game, it tells me my local save is newer than the one in the cloud and I get the sync option.. but other than this, it works.
Bit disappointing that EA cant sort this out, especially on such an awesome franchise with a cult following.
The 'Cloud' sucks and they should stop using it. They need to keep all of the save files on people's HDD so sh$% like this never happens. I'm tired of my game crashing every damn time I pass Kasumi's mission and then it just stops and won't let me by. EA needs to stop using the damn cloud because I have every one of my characters and saves on my HDD and I know exactly where they were. They're making problems that shouldn't exist when there were none to begin with. And her mission isn't the only one I have a problem with either... seems like all of the purchased DLC seems to have little problems like that in the middle of the battles too. EA needs to fix them or I'll be scared to death to think what a mess Andromeda's going to be like.
You can disable cloud save in Origin, either under "Application Settings" > "Install and Save" or in the Game settings. The cloud save feature also does not change the save games on your HDD if you not give explicit permission for it.
If you have problems with the DLCs I would suggest that you repair the game. (in Origin > Game Library > right click ME2 > Repair)
If your only big problem is the crash on the end of Kasumi's mission create a shortcut of the "Masseffect2.exe" on your desktop and add the parameter "-nomoviestartup" (without the quotes) at the end of the target line. (... Binaries\MassEffect2.exe" -nomoviestartup)
Then start the game from this shortcut.
