To try and figure out what's going it would help to have a DxDiag report in text format. Instructions on how to create a DxDiag report can be found here. Once the report is crated you can upload here by clicking the "Browse..." button at the bottom of the reply box (image below).
yeah already have all that ready so maybe you can see something
When it crashes does it go to the desktop or back to the MELE Launcher?
It goes back to the launcher and sometimes gives an error of memory can not be written but not everytime
I recall having a "memory can not be written" issue with a game once, but I don't think it was Mass Effect. This is what I remember doing at the time...
I've also done a number of searches with the information that you've provided to see if can find another solution, but I haven't found anything that isn't already listed in the threads linked to above.
The exact text of the error message may help pinpoint what the issues is.
