Need some advice from the game creators

Game creators probably won’t answer you, it’s evident that they don’t even know their own game or care, they are only interested in new ways to get your money. But I could give you my humble opinion. Don’t stress about the regions just upgrade utilities over time and eventually they’ll get back to where they were, the populations don’t count towards taxes, the capital is the most important.  omega buildings and utilities are your best bet (smallest footprint for more output)