I save my default load outs tab for gac/tw. I keep ideal mod sets on a second tab to make transitioning easy for specific events. A few character's load outs typically cover the major archetypes needed for various game modes: one defense tank set, one speed tank set, 3 top speed sets, best off/pot, best off/HP, best cc/cd. These sets stay on normal characters that transition to cover just about every aspect of the game without having to do a massive remod.
I remod all defaults about once a month.