In addition to possible compatibility issues, a mod is generally required to increase the allowable number of sliders or else no new ones or no sliders at all (even the built-in ones) will function once you get a sim into CAS and try to change something.
The usual candidates are NRaas MasterController, CmarNYC's XCAS, and AwesomeMod. If MC and XCAS are used together, some special handling is required or they may conflict with each other. XCAS and Awesome should never be used together.
Do you have one of these solutions in place already?