I use Nvidia Control Panel + Nvidia Inspector since inspector has a few more options but both work together. I'm not sure why the control panel conflicts with in-game settings for some but not all. The only problem I experience is screen tearing with a certain option enabled through Inspector but that's it. I have quite a few things adjusted with both.
My Control Panel settings:
Anisotropic filtering 16x
Antialiasing - Mode Override any application setting
Antialiasing - Setting 8x
Antialiasing - Transparency 8x (supersample)
Multi-Frame Sampled AA (MFAA) On
Power management mode Prefer maximum performance
Texture filtering - Quality High quality
Vertical sync On