I had it enabled in the beginning of playing the game but don't really remember how that looks now having had it disabled for a long time. It's quite easy getting life time points in game and the tips appeal to me more. I disabled because I always follow good advise (RAM-usage). The longest loading times for any long running game have been around 15 minutes and that was probably when I tired of it and searched for a solution. My game now is not nearly as long running as some of yours seem to be, and takes around a minute to load (on a SSD).