Hi
It could be that something has changed since the last time you played. I would back up your system, then cleanly uninstall TS3, reinstall the base game and patch it up to date. After that, test and make sure you can get it to work before adding expansions back in.
Clean uninstall/reinstall instructions
When you uninstall TS3 games on your Mac using the uninstaller, the game leaves behind stray files and isn't completely removed from your computer. These files may conflict with future installations. It is best to completely remove them. BluebellFlora's website provides a guide on how to do this:
http://bluebellflora.com/the-sims-3-on-a-mac/how-to-do-a-clean-uninstall-and-reinstall-on-a-mac/
After cleanly uninstalling, install the base game and patch it up to date. If you cannot update via the Launcher, download and apply the latest cumulative manual patch (called the superpatch) for Mac.
Check that your game works properly. Then install any EPs and SPs that you own, in order of release date.
