This was a fresh save and the CC was added after the facial effects started. All of my custom content is furniture so I see no reason why that would affect the Sims faces. I can try playing another save without the furniture and get back to you.
I played a new game without CC. This first girl was created in CAS with a normal nose as a child and aged up inside the game. She aged up with a bigger nose than I gave her in CAS. The second two were NPCs. They are all aging up with big noses/eyes and small chins/jaws. The two girls DID NOT lose any teeth and the boy DID lose teeth, so I'm not sure if it's related to the tooth bug. All I know is that when children age up, their eyes, nose, mouth, chin, or head change to bigger or smaller. It doesn't seem to matter if they are already in game as NPCs or created in CAS.
I had to fix my own Sims that I created in CAS when they aged up because they looked like this. This affects CAS Sims and NPC Sims.
