My sims can’t vacuum

bmoresvolcano​  You have a route block.  I can't tell if it is on the floor at the bottom of the stairs or the one above from your pic.  So, tell your sim to go to the tile at the bottom of the stairs.  If they have no problem, then so far so good.  Then, send the sim to the tile at the top of the stairs.  If they get that far, then have them go different places around the upper floor to see if you can find the blocked tile or tiles.  If you get a route block when you try to send the sim up the stairs, then it might be the roof causing the blockage.  So, try deleting all roofs you have on that floor.  If that is the problem, you'll have to rebuild the roof so that it doesn't intrude in the rooms using sections rather than a large roof that goes through any rooms.

If that is not the problem and you still can't figure it out, I will take a look at the lot to see if I can find the issue and give you a way to fix it.  All you need to do is upload the lot to the gallery and reply here with the lot name and your userid if different than the one you use here (bmoresvolcano).

Hope this helps.