Very interesting. Over all, it looks very promising. I do have a few concerns, though.
1) Sexuality opt in/opt out. Like Onverser, I like having a world without labels. I'd assume it'd be opt in like pronouns, but I still just hope I don't have to fight it.
2) Autonomous break ups: how is the event coded? If it is a random chance when having a poor relationship bar, that makes sense and has a prompt/limit. If it is just a random phone call or popup in the ever possible event pool, it will get under my skin so fast. Having all my long term relationships smashed in the name of drama is not worth it.