yeah, this is happening to me too. i haven't updated to the newest version (from a couple of hours ago iirc) so i'm not sure that fixed anything, but i've deleted a lot of CC from my folder including eyelashes, more traits, zerbu's mods, and other ones that were mentioned in this forum- yet, my CAS won't open in game when i right click + edit in CAS. it's very annoying and as someone who has A LOT of cc I've come to terms that i'll have to either wait for an update or sift through all of my cc files in a painstakingly annoying and long process.
my guess is that it's something supposedly innocuous like an accessory, clothing, or hair. i'm going to clear out all of my scripted mods again, and potentially post an update to see if it's one of those mods that is messing up my game.