Having more than 15 mods causes glitches in game
I've noticed while trying to debug my game that simply having more than 15 mods in my mods folder caused glitches in game. Social interactions like feeding toddlers and infants in a highchair, or trying to watch tv will cause my sims to t-pose glitch and drop the action from the queue. I'm not sure how many social interactions are affected, but I constantly have to monitor each of my sims to make sure they didn't glitch out of an action. I've tried different combinations of mods (typically clothing or hair to make sure it wasn't an issue with a script mod), and it keeps happening so I don't think it's just due to a broken mod. When I use Better Exceptions and MCCC I keep getting that it's some sort of constraint error, and no hints at any mods or cc being the issue.
Unfortunately, the only times I've seen this issue happen, the solution has started with uninstalling the game then reinstalling it from the EA App/Steam (whichever you use). I recommend also renaming your user folder and letting the game make a new one.