infinite loading screen

Hey, I don't know where else I can adress this issue, but its been a week and I have not been able to play. Everything was fine, until last sunday, since when I have been spending endless hours when I am at home just opening the game taking mods in and out, testing everything and I cant find the problem. I dont get LEs, but the game takes forever to load, then the save files take forever too and when I try to enter a lot via build mode it gets stuck on a loading screen again or even just the icon of the lot. Of course I havent even checked CAS bc it just won't load. This happens when I have all my mods in. I even took out about 200 of them and still have the problem. I am testing now with just cc but even with mods only, no cc it is very slow. I don't know if there is something wrong with my pc, maybe a virus that affects the system and it cant handle the same amount of mods suddenly(???) but from last saturday to last sunday it just changed and wouldn't load with the same mods in. It works ok without any mods btw. but no matter what mods I remove it is better, it doesnt seem to be a certain mod that is causing this. Do u have any idea what should I do?? Bc it is very weird that this happened basically in a night and I am guessing it might be related to the last update.