Cant click on certain things

First it was the sensitivity which I fixed with taking out reshade. but now after playing for only a few minutes the game keeps going but I cant click on the Inventory, Gallery, Phone, Calander, Aspiration, Skills, traits, and the option dots in the corner.The only way I can save my game is if I click on edit world and save game, it saves the game but it glitches it out completely Ive deleted and reinstalled origin. Ive deleted and reinstalled the sims. Ive taking out the game folder creating a new one. And I did the repair game option on Origin. Nothing is working at all and I dint know what to do. Please help me.