WheresWitz RJMarco23 Gotaluvsims koalabear1845 Veigh_D
As a test, please try playing in a clean user folder. Move the entire Sims 4 folder out of Documents > Electronic Arts and onto your desktop. When you launch the game, if it launches, a clean folder will spawn with no content. (Your saves and other content will be intact in the folder you've moved but temporarily unread by the game.) Don't add anything to the new folder yet; just start a new save and see how it runs, that is if you can get that far.
If this doesn't help, please provide a dxdiag. Click Windows key-R, enter dxdiag in the run box, wait for the scan to finish, click "Save all information," and save the file to your desktop. From there, you can attach it to a reply using the paper clip (Attachment) icon included with the other formatting buttons.
I would also be happy to see any of you (other than the OP) create your own thread posting a dxdiag and the results of the clean folder test. It's difficult to troubleshoot generic crashing issues with a number of people in one thread at the same time. And there are lots of reasons this game might crash, so it's unlikely that one suggestion will help more than one or two of you.