I'm having the same issue here. I'm a clean PC player. No mods or cc EVER. I can't take it, hoping I remember to save every 15 mins in case it crashes! I've verified all game files; there are no corruptions. I'm getting very frustrated. I hope this is fixed soon.
Update 2 days later: Still crashing every 20 mins or so. Or if you travel, then travel home, usually 5 mins later, guess what...crash. I've had to take a break from playing. I'm a somewhat seasoned player. Over 5,600 hours in PC gameplay alone. That's not counting Xbox time. Please fix this soon!
Update 7 days later: Thanks for the help puzzlezaddict . I think I have figured out my problem. This is my guess - I had too many items from too many different packs on one lot (the save I've been working on, I've been playing for 23 generations currently, so they have accumulated a lot of things over the years), and that was causing my game to overload and crash. I removed some things from various packs, and it isn't crashing nearly as much. I'm also thinking I need to upgrade my computer a bit, as I am running on a pretty basic setup.