Re: [MOD RELATED] Game not loading with origin

@AbC1428a8036907  It's easiest to deal with one issue at a time, so please put aside your entire Mods folder for now.  You can work with a new save instead of your existing ones if you prefer.

For the missing downloads, try repairing in Steam; the option is Properties > Local files > Manage integrity of the game files.  You can repair in Origin as well, but please test after only repairing in Steam.

The next step would be to do a clean uninstall and reinstall of Origin.  Clear its cache first and then uninstall it "the hard way":

https://help.ea.com/en-us/help/faq/clear-cache-to-fix-problems-with-your-games/

https://help.ea.com/en-us/help/origin/origin/manually-uninstalling-origin/

Reinstall using the full Origin installer (direct download link):

http://download.dm.origin.com/origin/live/OriginSetup.exe

Run the installer as an admin: right-click on the download and select "Run as administrator."  Restart your computer afterwards, and run both Steam and Origin as an admin too.